The city of Philadelphia was originally settled by the Dutch in 1633, but they abandoned it in about 1643. After that it switched hands a few times but ultimately the Dutch retook possession of it in 1655. By the end of the 17th century it was a major harbor for immigration. Many people came into Philadelphia as indentured servants coming over and working for the cost of their passage.
Did your relative come into the Colonies via Philadelphia? If so, there is A Health Officer's Register of Passenger's Names located in the State Archives. Check these records for your ancestor's name!